Job Title: Mammalian Cell Culture and Molecular Biology Technician

Reports to: CEO

Start date: Immediate

Contract term: Fixed-term, until March 31, 2027. Part-time - 2 or 3 days a week

Salary: £25K-£27K FTE per annum depending on qualifications and experience. This is a 0.6 FTE (3 days a week) or 0.4 FTE (2 days a week) role, pro rata.

Location of work: Sci-Tech Daresbury, Cheshire

Reason for role: support to deliver an Innovate UK project on the Next-Generation ADC Manufacturing platform

About Daresbury Proteins

Daresbury Proteins is an award-winning biotech start-up based in Warrington, specializing in mammalian recombinant protein production and cell line development. We focus on the R&D of "difficult-to-express" recombinant biologics produced in mammalian cells.

The Role

We are seeking a motivated Technician to support an Innovate UK project focused on a Next-Generation Antibody-Drug Conjugate (ADC) Manufacturing platform. Reporting directly to the CEO, you will assist in cloning experiments, transfections, and the day-to-day operations of our laboratory.

Key Responsibilities

* Molecular Biology: Clone and validate genetic elements in expression vectors for recombinant protein production.

* Cell Culture: Create stable and transient cell lines using various transfection approaches.

* Reporting: Maintain precise lab books and produce regular reports to track project progress.

* Lab Maintenance: Contribute to general lab housekeeping to ensure smooth internal operations.

* Collaboration: Communicate regularly with the CEO and team members to meet project deliverables.

Requirements & Qualifications

* Education: A degree in Cell/Molecular Biology, Biochemistry, or a related field.

* Experience: Proven hands-on experience in molecular biology and mammalian tissue culture.

* Technical Skills: Proficiency in maintaining adherent and suspension-grown cell lines (e.g., CHO, HEK293) and conducting expression analysis.

* Cloning: Confidence in restriction enzyme-based cloning techniques and data analysis.

* Soft Skills: Ability to work independently with high precision, motivation, and strong interpersonal skills.

* Data Literacy: Ability to interpret scientific data and maintain impeccable records.

How to Apply

Applicants must be eligible to work in the UK.

Please submit your CV, including full details of your training and research experience.

Include contact details for two referees (email and phone), one of whom must be your most recent line manager.

Please note: Due to the volume of applications, we are unable to notify unsuccessful applicants individually