Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges.

The Haniffa team is seeking an experienced Senior Staff Scientist to support the Haniffa Faculty Group in their generation of high quality iPSC and haematopoietic stem cell cultures for a permanent contract.

About the Team:

Muzlifah Haniffa is a dermatologist pioneering the applications of single cell genomics technologies to understand tissue homeostasis, immunity and disease pathogenesis. A major research goal of the Haniffa laboratory is to decode the development and functional maturation of the human immune system.

The Haniffa Group's research within the Cellular Genomics Programme applies disruptive cutting-edge techniques to study the genomics of immune cell populations at single-cell resolution and uses advanced computing capabilities to analyse data to reconstruct the immune system within its tissue context during development and adult life.

What you will be doing?

You will have the opportunity to guide , maintain and keep evolving at a high standard the wet laboratory haematopeoisis research of the Haniffa Lab. To help lead the team and partake to generate and validate data obtained from diverse single cell genomic projects. This involves:

1) supporting the generation of high quality iPSC and haematopoietic stem cell cultures (definitive and primitive haematopoiesis), single cell datasets and other wet lab protocols

2) helping to supervise lab members

3) work closely to engage internal and external stakeholders in the team's research

4) contribute to the research output and support the Group Leader as required

About you:

You will have a diverse range of research experiences and technical skills in experimental molecular/cellular biology including In Vitro models (such as 3D organoids and iPSC derived hematopoietic cells.

Essential Skills:

• PhD in a relevant wet-lab subject (e.g. Cell biology, Developmental Biology, Skin Biology, Immunology) or equivalent qualification in Biological Sciences - multiple projects
  
• Robust experience in maintaining hESC and/or hiPSC.
  
• Experience in handling, processing and storing human cells and tissues.
  
• Strict adherence to SOPs and attention to detail when performing routine tasks.
  
• Experience in flow cytometry, immunocytochemistry, routine imaging.
  
• Ability to test, implement and troubleshoot new approaches and techniques.
  
• Experience in single cell transcriptomic and producing cDNA libraries.
  
• Thorough record keeping, with strong organisational and communication skills, and good work
  
• ethic.
  
• Motivation and ambition to make a personal contribution to the team and the GRL research.
  
• A team player who enjoys working with others in a friendly and collegiate manner.
  
• Ability to build collaborative working relationships with internal and external stakeholders.
  

Other Information:

Salary per annum (dependent upon skills and experience): £53,717-£63,815

Application Process:

Please apply with your CV and a Cover Letter (up to two pages each) outlining how you meet the criteria set out above.

Closing Date: 14th August 2025

Hybrid Working at Wellcome Sanger:

We recognise that there are many benefits to Hybrid Working; including an improved work-life balance, with more focused time, as well as the ability to organise working time so that collaborative opportunities and team discussions are facilitated on campus. The hybrid working arrangement will vary for different roles and teams. The nature of your role and the type of work you do will determine if a hybrid working arrangement is possible.

Equality, Diversity and Inclusion:

We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world. We have a supportive culture with the following staff networks, LGBTQ+, Parents and Carers, Disability and Race Equity to bring people together to share experiences, offer specific support and development opportunities and raise awareness. The networks are also a place for allies to provide support to others.

We want our people to be whoever they want to be because we believe people who bring their best selves to work, do their best work. That's why we're committed to creating a truly inclusive culture at Sanger Institute. We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Our Benefits:

We are proud to deliver an awarding campus-wide employee wellbeing strategy and programme. The importance of good health and adopting a healthier lifestyle and the commitment to reduce work-related stress is strongly acknowledged and recognised at Sanger Institute.

Sanger Institute became a signatory of the International Technician Commitment initiative In March 2018. The Technician Commitment aims to empower and ensure visibility, recognition, career development and sustainability for technicians working in higher education and research, across all disciplines.