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DATE ADDED: Wed 20/11/2019

Postdoctoral Fellow In Parasitic Diseases: Drug Discovery And Therapeutics

Chicago, IL, US
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COMPANY: LOYOLA UNIVERSITY CHICAGO

JOB TYPE: Permanent, FullTime

Postdoctoral Fellow in Parasitic Diseases: Drug Discovery and Therapeutics
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Please see Special Instructions for more details.
Interested applicants should submit a cover letter, CV and contact information of three references to: #removed#










Position Details















Position Details









Job Title
Postdoctoral Fellow in Parasitic Diseases: Drug Discovery and Therapeutics






Position Title
Postdoctoral Fellow in Parasitic Diseases: Drug Discovery and Therapeutics






Position Number







Job Category
University Faculty






Job Type
Full-Time






FLSA Status
Exempt






Campus
Maywood-Health Sciences Campus






Location Code
DEPARTMENT OF MEDICINE (06500A)






Department Name







Is this split and/or fully grant funded?







Duties and Responsibilities


Searching for a post-doctoral research fellow in the Department of Medicine, Loyola University Medical Center, Chicago, USA. Our primary focus is to develop high throughput screening methods for identifying lead compounds using new drug libraries, synthetic molecules, approved drugs and natural products for treating protozoan diseases, specifically Malaria, Leishmaniasis, Chagas disease and Toxoplasmosis. These parasites are still continuing to be threat globally, currently no vaccines and treatment primarily depended on pharmacotherapy. Rapid emergence of drug resistance to commonly used drugs, coupled with limited availability of second-line therapeutics creates an immediate need to discover new and effective drugs. Besides the problem of drug resistance and toxicity, currently used drugs cause adverse effects on the host immune system (immune dysregulation). Therefore, our approach is to discover and develop drugs that target parasite as well have beneficial effect on the host immune response. Furthermore, we will utilize in-silico analysis, including molecular docking and structure-based screening to identify putative targets, mechanisms of actions of each lead compounds and in-vitro enzymatic assays to validate. Our lab is also interested in understanding the molecular and biological mechanisms underlying anemia caused by inflammation using an in-vitro erythropoiesis model.








Qualifications


We seek highly motivated researcher with previous experience of working with at least one of the parasite, drug discovery and/or therapeutic development areas. Required skills include tissue culture, parasite culture, in-vitro screening in parasites, flow cytometry, RT-PCR, microscopy imaging, functional enzymatic assays and related molecular biology techniques. Applicants should have excellent writing skills and able to work both independently and collaboratively. Applicants should have a Ph.D. (or expected to receive a Ph.D.) in the biomedical sciences or M.D. equivalent at the time of joining the lab.








Physical Demands







Working Conditions







Minimum Education and/or Work Experience


Searching for a post-doctoral research fellow in the Department of Medicine, Loyola University Medical Center, Chicago, USA. Our primary focus is to develop high throughput screening methods for identifying lead compounds using new drug libraries, synthetic molecules, approved drugs and natural products for treating protozoan diseases, specifically Malaria, Leishmaniasis, Chagas disease and Toxoplasmosis. These parasites are still continuing to be threat globally, currently no vaccines and treatment primarily depended on pharmacotherapy. Rapid emergence of drug resistance to commonly used drugs, coupled with limited availability of second-line therapeutics creates an immediate need to discover new and effective drugs. Besides the problem of drug resistance and toxicity, currently used drugs cause adverse effects on the host immune system (immune dysregulation). Therefore, our approach is to discover and develop drugs that target parasite as well have beneficial effect on the host immune response. Furthermore, we will utilize in-silico analysis, including molecular docking and structure-based screening to identify putative targets, mechanisms of actions of each lead compounds and in-vitro enzymatic assays to validate. Our lab is also interested in understanding the molecular and biological mechanisms underlying anemia caused by inflammation using an in-vitro erythropoiesis model.




We seek highly motivated researcher with previous experience of working with at least one of the parasite, drug discovery and/or therapeutic development areas. Required skills include tissue culture, parasite culture, in-vitro screening in parasites, flow cytometry, RT-PCR, microscopy imaging, functional enzymatic assays and related molecular biology techniques. Applicants should have excellent writing skills and able to work both independently and collaboratively. Applicants should have a Ph.D. (or expected to receive a Ph.D.) in the biomedical sciences or M.D. equivalent at the time of joining the lab.




Interested applicants should submit a cover letter, CV and contact information of three references to: #removed#








Open Date
12/14/2018






Close Date







Special Instructions to Applicants


Interested applicants should submit a cover letter, CV and contact information of three references to: #removed#








Quick Link for Posting
#removed#/postings/9915






Job Number







Organizational Location
Provost Health Sciences Division


















Posting Details















Posting Detail









Number of Vacancies
1






Desired Start Date







Position End Date







Open Until Filled
Yes
















Applicant Documents



Required Documents





+ Curriculum Vitae






Optional Documents





+ Cover Letter/Letter of Application




+ Teaching Statement




+ Research Statement




+ Writing Sample




+ Scholarly Publications




+ Teaching Evaluations




+ Other Document




+ Unofficial Transcripts




+ Multi Media




+ Resume
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